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Generic Statins a Good Alternative to Expensive Lipitor, Consumer
Reports Says
Date Published: Tuesday, February 19th, 2008AddThis Social Bookmark Button
 

Lipitor is the top-selling prescription drug in the world and
Americans spent over $6.5 billion on Lipitor in 2006 alone. Lipitor’s
maker—Pfizer—is spending millions on a marketing campaign to keep
Lipitor at number one. But Lipitor is not the only option available
for the treatment for high cholesterol, and a new report by Consumer
Reports says that many less expensive generic cholesterol treatments
work just as well as Lipitor.
Consumer Reports says Lipitor’s compelling ads with Dr. Robert
Jarvik—inventor of the Jarvik artificial heart—may lead consumers to
believe Lipitor to be the only statin that can lower cholesterol.
According to Consumer Reports, Lipitor is—in fact—a highly effective
drug for lowering cholesterol and it’s one good choice for people who
have high levels of LDL cholesterol or who’ve had a heart attack or
who suffer from acute coronary syndrome (ACS). What consumers may not
know is that the vast majority of people can get the same protection
of Lipitor from a generic statin at less than half the cost.

Generic drugs are chemical twins of brand-name drugs whose patents
have expired. Three generic statins now available are: Simvastatin,
pravastatin, and lovastatin. Lipitor’s Web site makes a point of
saying that there is “no generic form of Lipitor”; however, there will
be Lipitor generics in two years when its patent expires. Another good
reason why Pfizer is spending lots of money now to ensure brand name
Lipitor stays with consumers.
Statins are a class of drugs that lower the level of cholesterol in
the blood by reducing the production of cholesterol by the liver,
blocking the enzyme in the liver responsible for producing
cholesterol. Cholesterol is critical to the normal function of every
cell in the body; however, it also contributes to the development of
atherosclerosis, a condition in which cholesterol-containing plaques
form within the arteries. These plaques block the arteries and reduce
the flow of blood to the tissues that the arteries supply. When
plaques rupture, a blood clot forms on the plaque further blocking the
artery and reducing blood flow. When blood flow is reduced
sufficiently in the arteries that supply blood to the heart, the
result is angina or heart attack; if on plaques in the brain, the
result is stroke; on plaques in the leg, intermittent
claudication—pain in the legs while walking. By reducing cholesterol
production, statins slow the formation of new plaques and can
occasionally reduce existing plaque size. Statins also stabilize
plaques and make them less prone to rupturing and forming clots.

Lipitor’s patient information does not list cognitive issues among its
side effects; however, anecdotal reports linking statins—like
Lipitor—to mental problems are beginning to gain some attention. Some
doctors are concerned that statins, specifically Lipitor, might help
patients’ hearts but jeopardize their minds. To be certain,
researchers at the University of California at San Diego are
completing a randomized, controlled trial examining the effect of
statins on thinking, mood, behavior, and quality of life. Concerns
about statins on cognition have appeared in medical journals,
conferences, and the mainstream media for years and there has been
talk linking statins to the development of diseases such as
amyotrophic lateral sclerosis (ALS)—Lou Gehrig’s disease—and
Parkinson’s disease.
<

This entry was posted on Tuesday, February 19th, 2008 at 11:39 am and
is filed under Legal News, Pharmaceuticals.
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One Response to “Generic Statins a Good Alternative to Expensive
Lipitor, Consumer Reports Says”
1. Jorge Paraliticci Says:
  May 27th, 2009 at 3:22 am

I have been using Lipitor 10 since April 2005. At that moment my
Colesterol was 245, HDL 36, LDL 169. My last Lipid Profile was
last March, with the Colesterol 178, HDL 52, LDL 110.I started
going to the Gym 1 hour 4 days a week and I notice that the
reading for the AST whent up 55 as well as ALT 60, Can you let me
know it is cause by the additional excersice. I consulted with my
Doctor and he recommended to stop the Lipitor for a month and have
a new Lipod Profile to verify the result.
Please advice.

Best regsrds.
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