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News on Avandia, Rosiglitazone (generic) continually updated from thousands of sources around the net. ----------------------------------------------------------------- Saturday PharmaGossip
EHJ editors rebuffed GSK efforts to suppress Nissen editorial on rosiglitazone A CardioBrief The editors of the European Heart Journal rejected a request by a senior GSK executive to suppress an editorial written by Steve Nissen about rosiglitazone .
Comment? Related Topix: Medicine, Medication
Avandia, Rosiglitazone Talk =========================== Recent Avandia, Rosiglitazone Discussions
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Fri Apr 30, 2010 The American Journal of Managed Care
Clinical Consequences of Disseminating the Rosiglitazone FDA Safety Warning Published Online: May 1, 2010 - 12:00:01 AM Background : On May 21, 2007, a safety alert was widely disseminated through the media and US Food and Drug Administration MedWatch concerning a possible increased risk of ischemic myocardial infarction and cardiovascular death in people receiving the antidiabetic drug rosiglitazone.
Comment? Related Topix: Food and Drug Administration, Medicine
Thu Apr 29, 2010 The Motley Fool
Earnings Up 17%, but Here's Why You Should Be Worried It was a rather gloomy first-quarter report from GlaxoSmithKline , considering that revenue was up 9% and adjusted earnings per share shot up 17%. Unfortunately, most of that gain came from sales of pandemic vaccine and antiviral treatment Relenza.
Comment? Related Topix: Biotech, GlaxoSmithKline, H1N1 Influenza / Swine Flu, Health, Medicine, Influenza, Bird Flu, Diabetes, Medication
Wed Apr 28, 2010 A Georgia Lawyer
GA Avandia: TIDE Trial From: http://www.theheart.org/article/1069095.do Looks like folks will have to wait until July of 2010 to see if the Thiazolidinedione Intervention with Vitamin D Evaluation trial, commissioned by the FDA and pitting rosiglitazone against pioglitazone , will be allowed to continue.
Comment? Related Topix: Healthcare Law, Law, Medicine, Medication, Actos, Pioglitazone (generic)
PharmaGossip Testimony of Sidney M. Wolfe, M.D. Director, Health Research Group at Public Citizen - Avandia
The TIDE trial continues to recruit patients despite a lack of clinical equipoise, exposing thousands of high-risk patients with diabetes to a drug with an unfavorable safety profile and no clinical advantage over its comparator. Comment?
Related Topix: Medicine, Medication, Health, Diabetes MSNBC
Public health advocate wants Avandia study halted A leading public health advocate pressed his case Wednesday to halt a trial of GlaxoSmithKline's diabetes drug Avandia, telling a House subcommittee the pill needlessly increases patients' heart attack risk.
Comment? Related Topix: Medicine, Medication, Healthcare Law, Law, Diabetes, Health, Food and Drug Administration, Actos, Pioglitazone (generic), Rosa DeLauro, US Politics, US News, US House of Representatives, Democrat
Mon Apr 26, 2010 Circulation
Thiazolidinedione Drugs and Cardiovascular Risks: A Science Advisory... Key Words: AHA/ACCF Science Advisory diabetes cardiovascular diseases myocardial infarction risk factors Introduction The purpose of this science advisory is to summarize the currently available data concerning thiazolidinediones and cardiovascular risk, with a focus on ischemic heart disease events, and to provide practical recommendations ...
Comment? Related Topix: Medicine, Diabetes, Health, Food and Drug Administration, Medication
The Post Chronicle Scientists Find New Protein Key To Bowel Disease
Using drugs or diet to boost a protein to restore the body's natural defenses to gut infections may offer a new way to treat currently incurable bowel diseases such as Crohn's disease, European scientists said on Monday. Comment?
Related Topix: Crohn's Disease, Health, France, World News, Medicine, Diabetes, Medication, Actos, Pioglitazone (generic) Wed Apr 21, 2010
Circulation Oral Intake of Rosiglitazone Promotes a Central Antihypertensive...
Hypertension. 2010 Published online before print April 19, 2010, doi: 10.1161/HYPERTENSIONAHA.109.149146 Submitted on December 14, 2009 Revised on January 7, 2010 Oral Intake of Rosiglitazone Promotes a Central Antihypertensive Effect Via Upregulation of Peroxisome Proliferator-Activated Receptor- and Alleviation of Oxidative Stress in Rostral ... Comment?
Related Topix: Medicine, Medication, Taiwan, Southeast Asia, World News Mon Apr 19, 2010
Philly.com Check Up: FDA reconsiders diabetes drug study
The U.S. Food and Drug Administration reportedly is considering suspending a safety review of the GlaxoSmithKline diabetes drug Avandia because of concerns that patients on the medication are at unnecessary risk for heart attacks and other heart problems. Comment?
Related Topix: Healthcare Law, Food and Drug Administration, Law, Medicine, Diabetes, Health, Medication, Biotech, GlaxoSmithKline, Healthcare Industry Fri Apr 16, 2010
Circulation
PPAR{gamma} Activation Prevents Hypertensive Remodeling of Cerebral...Activation Prevents Hypertensive Remodeling of Cerebral Arteries and Improves Vascular Function in Female Rats Marilyn J. Cipolla PhD; Nicole Bishop BS; R. Saman Vinke BS; and Julie A. Godfrey BS From the Departments of Neurology, Obstetrics, Gynecology & Reproductive Sciences and Pharmacology, University of Vermont, Burlington, Vt. Comment?
Related Topix: University of Vermont, Burlington, VT, Medicine, Medication Mon Apr 12, 2010
The New York Times Study Sees a Slant in Articles on Drug
A new analysis of reviews and articles about the controversial diabetes drug Avandia has found that experts who were paid by its manufacturer have been significantly more likely than others to draw positive conclusions about the drug's safety and efficacy. Comment?
Related Topix: Medication, Diabetes, Health Sat Apr 10, 2010
Kevin, M.D. Statistical analysis in medical journals should be unbiased
Editors of medical journals should unite in requiring independent statistical analyses of industry-sponsored clinical trials, according to the two top editors of the Journal of the American Medical Association . Comment?
Related Topix: Mathematics, Science, Medicine, Medication, Healthcare Law, Law Fri Apr 09, 2010
PharmaGossip GSK - Avandia: The Lancet wades in
The story of rosiglitazone is one of death, greed, and corruption, according to the Staff Report of the United States Senate Committee on Finance, released on Feb 20, 2010. Comment?
Related Topix: Medicine, Medication, Biotech, GlaxoSmithKline, Healthcare Law, Law, Food and Drug Administration Tue Apr 06, 2010
Archives General Psychiatry Evidence From Randomized Controlled Trials, Meta-analyses, and Subgroup Analyses Letters
To the Editor: Drs Hennekens and DeMets1 argued that large RCTs designed to test a priori hypotheses are the best strategy to detect small to moderate benefit or harm from drugs. Comment?
Related Topix: Medicine, Medication Mon Apr 05, 2010
Medical News Today More News From The Journal Of Clinical Investigation: April 1, 2010
METABOLIC DISEASE: Differential drug response in lean and obese patients explained One thing that predisposes individuals who are obese to type 2 diabetes is the persistent, low-level inflammation that results, in part, from dysregulation of the function of white fat tissue in the abdominal cavity between the internal organs . Comment?
Related Topix: Diabetes, Health, Medication Sat Apr 03, 2010
Science Daily Metabolic disease: Differential drug response in lean and obese patients explained
One thing that predisposes individuals who are obese to type 2 diabetes is the persistent, low-level inflammation that results, in part, from dysregulation of the function of white fat tissue in the abdominal cavity between the internal organs . Comment?
Related Topix: Medicine, Diabetes, Health, Philippe Lefebvre, Medication Email me Avandia, Rosiglitazone news. Learn more
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