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Katherine Zeratsky, R.D., L.D.
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Biography of
Katherine Zeratsky, R.D., L.D.

photo of Katherine Zeratsky, R.D., L.D. Katherine Zeratsky, R.D.,
L.D.
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As a specialty editor for the Food & Nutrition Center, Katherine
Zeratsky helps you sort through the facts and figures, the fads
and the hype to learn more about nutrition and diet.
A Marinette, Wis., native, she is certified in dietetics by the
state of Minnesota and the American Dietetic Association. She has
been with Mayo Clinic since 1999.

She is active in nutrition-related curriculum and course
development in pediatrics at Mayo Clinic Rochester and nutrition
education related to the physiology and recommended intakes for
premature infants.
Other areas of interest include breast milk and formula safety,
neonatal feeding, and nutrition for breast-feeding mothers.

She graduated from the University of Wisconsin-Madison, served a
dietetic internship at the University of Iowa Hospitals and
Clinics, and worked as a registered dietitian and health risk
counselor at ThedaCare of Appleton, Wis., before joining the Mayo
Clinic staff.
 

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Vitamin D toxicity: What if you get too much?

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Question
--------

Vitamin D toxicity: What if you get too much?
What is vitamin D toxicity, and should I worry about it since I take
supplements?
--------------------------------------------------------------------

Answer
------
from Katherine Zeratsky, R.D., L.D.

Vitamin D toxicity, also called hypervitaminosis D, is a potentially
serious but treatable medical condition that occurs when you get too
much vitamin D.
Vitamin D toxicity usually results from taking an excessive amount of
vitamin D supplements — not from your diet or too much sun exposure.
That's because your body produces only a limited amount of vitamin D
from sun exposure, and even fortified foods don't contain large
amounts of vitamin D. Although vitamin D toxicity is rare even among
people who take supplements, you may be at greater risk if you have
health problems, such as liver or kidney conditions, or if you take
thiazide-type diuretics.

The main consequence of vitamin D toxicity is a buildup of calcium in
your blood (hypercalcemia), causing symptoms such as:
Nausea

Vomiting
Poor appetite

Constipation
Weakness

Confusion
Heart rhythm abnormalities

Kidney stones
Treatment of vitamin D toxicity may include:

Stopping vitamin D supplements
Restricting calcium intake

Medications
Hydration with fluids

Hospitalization in severe cases
Vitamin D is an essential nutrient. The Institute of Medicine
recommends that children and adults up to age 50 get 200 international
units (IU) of vitamin D daily. The recommendation for adults over age
50 is 400 to 600 IU daily. However, many health experts consider these
recommendations to be too low. The American Academy of Pediatrics, for
instance, now recommends that children and adolescents get 400 IU of
vitamin D daily. Many experts now "unofficially" recommend that adults
get as much as 1,000 to 2,000 IU of vitamin D daily. In addition, it's
likely that the vitamin D guidelines will be revised upward.

Supplements can be a reasonable way to meet recommended levels — as
long as you pay attention to how much you take. And be sure to tell
your doctor about any supplements you take.
Next question

Prenatal vitamins: OK for women who aren't pregnant?
 

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Chocolate: Does it impair calcium absorption?
Vitamin C: Can too much be harmful?

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Related Links

References
1. Leu JP, et al. Vitamin D toxicity: Caveat emptor. Endocrine
  Practice. 2008;14:1188.

2. Hemmelgarn M. Shedding light on vitamin D. American Journal of
  Nursing. 2009;109:19.
3. Lee JH, et al. Vitamin D deficiency: An important, common, and
  easily treatable cardiovascular risk factor? Journal of the
  American College of Cardiology. 2008;52:1949.

4. Dietary supplement fact sheet: Vitamin D. Office of Dietary
  Supplements. National Institutes of Health.
  http://ods.od.nih.gov/factsheets/vitamind.asp. Accessed June 2,
  2009.
5. Hathcock JN, et al. Risk assessment for vitamin D. American
  Journal of Clinical Nutrition. 2007;85:6.

6. Brannon PM, et al. Overview of the conference "Vitamin D and
  Health in the 21st Century: An Update." American Journal of
  Clinical Nutrition. 2008;88(suppl):483S.
7. Vitamin D. The Merck Manuals: The Manual for Healthcare
  Professionals. http://www.merck.com/mmpe/sec01/ch004/ch004k.html.
  Accessed May 21, 2009.

8. Wagner CL, et al. Prevention of rickets and vitamin D deficiency
  in infants, children and adolescents. Pediatrics. 2008;122:1142.
9. Hensrud DD (expert opinion). Mayo Clinic, Rochester, Minn. June
  17, 2009.

AN02008
Aug. 22, 2009

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