Information about crestor vs lipitor
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Crestor vs. Lipitor =================== Many people may wonder what the difference is between Lipitor versus Crestor. While both medications are statins and are effective for lowering cholesterol, there are some differences. Lipitor is known to interact with grapefruit juice, but there are no dietary restrictions for Crestor. One short study showed that Crestor was more effective than Lipitor, but more research is needed to confirm these findings.
Comparing Lipitor and Crestor: An Overview ------------------------------------------
Lipitor® (atorvastatin calcium) and Crestor® (rosuvastatin calcium) are both cholesterol medications. They are quite similar in many aspects; however, there are a few important differences between the two medications. Crestor Versus Lipitor: The Similarities ----------------------------------------
Both Crestor and Lipitor belong to a class of drugs called statins
(also known as HMG-CoA reductase inhibitors). Statins work by blocking
a particular enzyme, HMG-CoA reductase, that controls the rate of
cholesterol production in the body. This causes the liver to make less
cholesterol. Both medications are very effective for lowering
cholesterol. Crestor side effects and Lipitor side effects are
similar, and both medications carry similar warnings and precautions
(see Crestor Precautions and Warnings and Lipitor Precautions and
Warnings). In addition, both drugs should not be taken during
pregnancy. Both drugs are approved to treat high cholesterol, high
triglycerides, and low HDL cholesterol ("good" cholesterol). Both are
also approved to prevent heart attacks, strokes, and certain heart
procedures (such as bypass surgery) in people who do not yet have
heart disease but who have certain risk factors for heart disease.
Both medications are currently available only in brand-name form,
although it is very likely that Lipitor will "go generic" before
Crestor, since Lipitor is an older medication.
(Crestor vs. Lipitor Continued: Page 2)Advertisement List of references (click here)
Crestor package insert. Wilmington, DE: AstraZeneca Pharmaceuticals LP;2010 February. AstraZeneca Pharmaceuticals. First head to head study comparing CRESTOR® and LIPITOR® effects on the treatment of atherosclerosis (1/15/2008). AstraZeneca Web site. Available at: http://www.astrazeneca.com/Pressrelease/5369.aspx. Accessed November 11, 2008.
Lipitor package insert. New York, NY: Pfizer, Inc.; 2007 November. Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD Last reviewed by: Kristi Monson, PharmD;
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