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Order Generic Hyzaar
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Order Losartan + Hydrochlorothiazide (generic Hyzaar)
-----------------------------------------------------
Brand Name

Hyzaar
Generic Name

Losartan + Hydrochlorothiazide
Category

High Blood Pressure
Medication

50-12.5 , 100-12.5 mg
Information to have about Losartan + Hydrochlorothiazide (Generic
Equivalent to Hyzaar) . .

What is Losartan-Hydrochlorothiazide (Generic Hyzaar) and what are its
uses?
How does Losartan-Hydrochlorothiazide (Generic Hyzaar) treat?
Dosage: How should you take Losartan-Hydrochlorothiazide (Generic
Hyzaar)?
Effect of other drugs consumed with Losartan-Hydrochlorothiazide
(Generic Hyzaar)
What should you watch for while taking Losartan-Hydrochlorothiazide
(Generic Hyzaar)?
Possible Side effects of Losartan-Hydrochlorothiazide (Generic Hyzaar)
Order Losartan + Hydrochlorothiazide - Generic Equivalent to Hyzaar

Category :
High Blood Pressure

Medication
Quantity

Price USD
Order

Losartan 50 mg - Hydrochlorothiazide 12.5 mg
Generic Equivalent to Hyzaar 50-12.5mg
30

1.18
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60

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90

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Losartan 50 mg - Hydrochlorothiazide 12.5 mg
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120

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Medication
Quantity

Price USD
Order

Losartan 100 mg - Hydrochlorothiazide 12.5 mg
Generic Equivalent to Hyzaar 100-12.5mg
30

1.78
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---------------------------------------------------------------------
What is Losartan-Hydrochlorothiazide (Generic Hyzaar) and what are its
uses?

Hyzaar is a combination of Losartan and Hydrochlorothiazide used to
lower blood pressure.
Hydrochlorothiazide is a thiazide diuretic (water pill).
Hydrochlorothiazide increases the amount of water and salt you lose in
your urine. Hydrochlorothiazide is used to lower blood pressure and to
decrease edema (swelling).

Losartan controls high blood pressure (hypertension) by relaxing blood
vessels.
Hyzaar is effectively used to reduce hypertension (high blood
pressure) and for the reduction of stroke risk in patients with
hypertension and left ventricular hypertrophy.

Top
How does Losartan-Hydrochlorothiazide (Generic Hyzaar) treat?

Hyzaar tablets are a combination of Hydrochlorothiazide and Losartan
potassium.
Hydrochlorothiazide belongs to the group of drugs known as thiazide
diuretic. Thiazide diuretics act in the kidney, where they increase
the production of urine. Hydrochlorothiazide increases the removal of
salts from the blood, it thereby causes more water to be drawn out of
the blood and into the urine. Removing water from the blood decreases
the volume of fluid circulating through the blood vessels, which
lowers the pressure within the blood vessels, i.e. lowers blood
pressure. Hydrochlorothiazide also decreases the effort required by
the heart to pump the blood around the body.

Losartan is a type of medicine called an angiotensin II receptor
antagonist. Losartan works by preventing the action of a hormone in
the body called angiotensin II. Angiotensin II normally acts on
special receptors in the body, with two main results. Losartan causes
the peripheral blood vessels to narrow, and it also stimulates the
production of another hormone called aldosterone. Aldosterone causes
salt and water to be retained by the kidneys, which increases the
volume of fluid in the blood vessels. Losartan blocks the receptors
that angiotensin II acts on, and so prevents its actions. The main
result of this is that the peripheral blood vessels are allowed to
widen, which means that there is more space and less resistance in
these blood vessels. This helps lower blood pressure.
The combination of these two medicines is particularly useful in
treating high blood pressure.

Hyzaar has also been shown to reduce the risk of stroke in people who
have high blood pressure together with an enlargement in the left side
of their heart. People with both these conditions may therefore been
prescribed Hyzaar to reduce their chances of experiencing a stroke.
However, Hyzaar is not effective for this particular use in black
patients.
Top

Dosage: How should you take Losartan-Hydrochlorothiazide (Generic
Hyzaar)?
Take Hyzaar tablets orally.

Swallow the Hyzaar tablets with a drink of water. Hyzaar can be taken
with or without food.
Adults
The usual starting dose of Hyzaar is one 50-12.5 tablet per day.

If your blood pressure does not respond to this dose, after about 3
weeks the doctor may increase the dose of Hyzaar.
Children
The safety and effectiveness of Hyzaar in children have not been
established.

Have you skipped your Hyzaar dose?
If you miss a dose of Hyzaar, take it as soon as you can. If it is
almost time for your next dose, take only that dose of Hyzaar. Do not
take double or extra doses of Hyzaar.
---------------------------------------------------------------------
If you take too much of Hyzaar?
Incase of an overdose with Hyzaar seek medical emergency immediately.

Symptoms of Hyzaar overdose may include
dizziness,

weakness,
fainting, and

fatigue
Where should you store Hyzaar?
Store Hyzaar in a well-closed container which small children will not
be able to open.

Store Hyzaar at a temperature between 15 and 30 degrees C (59 and 86
degrees F). Protect Hyzaar from heat and light. Throw away any unused
amount of Hyzaar after the expiry date.
Available strengths of Hyzaar
Hyzaar tablets are available in the strengths of 50/12.5 mg (50
milligrams of Losartan and 12.5 milligrams of Hydrochlorothiazide) and
100/12.5 mg (100 milligrams of Losartan and 12.5 milligrams of
Hydrochlorothiazide).

Top
Effect of other drugs consumed with Losartan-Hydrochlorothiazide
(Generic Hyzaar)

If Hyzaar is taken with other medicines that lower blood pressure, the
effect on blood pressure may be enhanced. This may cause dizziness and
on rare occasions, fainting when moving from sitting or lying to a
sitting or standing position. Other medicines that reduce blood
pressure include the following:
other high blood pressure treatments (antihypertensives) such as
 beta-blockers, alpha-blockers, diuretics

narcotics
barbiturates.

Hydrochlorothiazide in Hyzaar can decrease the amount of potassium in
the blood. If Hyzaar is taken with other medicines, which can lower
blood potassium, this effect may be enhanced. Such medicines include
the following:
other diuretics

amphotericin
corticosteroids

carbenoxolone
beta agonist bronchodilators such as salbutamol.

Losartan in Hyzaar may increase blood potassium levels. If Hyzaar is
taken with other medicines that can increase blood potassium, this
effect may be enhanced. Such medicines include the following:
potassium-sparing diuretics such as spironolactone

potassium supplements
potassium containing salt substitutes.

Your blood potassium level should be monitored if you take any
medicines that can affect potassium in combination with Hyzaar.
Non-steroidal anti-inflammatory drugs (NSAIDs), such as indomethacin,
may oppose the blood pressure lowering effect of Hyzaar and may
increase the risk of side effects on the kidneys.

Hyzaar may increase blood levels of the medicine lithium, and Hyzaar
is therefore not recommended for people taking lithium. If it is
necessary to take both, your doctor should carefully monitor your
blood levels of lithium.
Hydrochlorothiazide in Hyzaar may raise blood glucose levels. People
with diabetes should therefore carefully monitor their blood sugar
while taking Hyzaar, as the effectiveness of antidiabetic medicines
may be reduced. This effect may be enhanced if you are also taking
diazoxide. Dose adjustments of your antidiabetic medicine may be
required. Discuss this with your doctor.

Hydrochlorothiazide in Hyzaar can increase blood calcium levels. If
you are also taking calcium or vitamin D supplements your blood
calcium level should be monitored.
Hyzaar should not be taken within four hours of the following
medicines, as if they are taken at the same time they may reduce the
absorption of Hydrochlorothiazide from the gut:

colestipol
colestyramine.

The following medicines may reduce the effect of Losartan in Hyzaar:
fluconazole

rifampicin.
Who should not take Hyzaar?
When pregnancy is detected, Hyzaar should be discontinued as soon as
possible.

The use of Hyzaar during the second and third trimesters of pregnancy
has been associated with fetal and neonatal injury, including
hypotension, neonatal skull hypoplasia, anuria, reversible or
irreversible renal failure, and death.
Prematurity, intrauterine growth retardation has also been reported.

It is not known whether Hyzaar is excreted in human milk, however
significant levels of both the compounds have been shown to be present
in the milk of lactating rats. A decision should be made whether to
discontinue nursing or discontinue Hyzaar, taking into account the
importance of the drug to the mother.
Hyzaar should not be used if you suffer from severely decreased kidney
or liver function, failure of the kidneys to produce urine, decreased
volume of fluid in the body, severe vomiting or diarrhoea.

Hyzaar should not be used if you are allergic to any
sulfonamide-derived drugs.
Hyzaar should not be used if you are allergic to one or any of its
ingredients. Please inform your doctor or pharmacist if you have
previously experienced such an allergy.

If you feel you have experienced an allergic reaction, stop using
Hyzaar and inform your doctor or pharmacist immediately.
Top

What should you watch for while taking Losartan-Hydrochlorothiazide
(Generic Hyzaar)?
Check your blood pressure regularly while you are taking Hyzaar. Ask
your prescriber or health care professional what your blood pressure
should be and when you should contact him or her. When you check your
blood pressure, write down the measurements to show your prescriber or
health care professional. You must not get dehydrated. Ask your
prescriber or health care professional how much fluid you need to
drink a day. If you are taking Hyzaar for a long time, you must visit
your health care professional for regular checks on your progress.
Make sure you schedule appointments on a regular basis.

Check with your prescriber or health care professional if you get an
attack of severe diarrhea, nausea and vomiting, or if you sweat a lot.
The loss of too much body fluid can make it dangerous for you to take
Hyzaar.
You may get dizzy. Do not drive, use machinery, or do anything that
requires mental alertness until you know how Hyzaar affects you. To
avoid dizzy or fainting spells, do not stand or sit up quickly.
Alcohol may increase the possibility of dizziness. Avoid alcoholic
drinks until you have discussed their use with your prescriber or
health care professional.

If you are going to have surgery tell your prescriber or health care
professional that you are taking Hyzaar.
Hyzaar may affect your blood sugar level. If you have diabetes, check
with your prescriber or health care professional before changing the
dose of your diabetic medicine.

Avoid salt substitutes unless you are told otherwise by your
prescriber or health care professional. Do not take medicines for
appetite control, asthma, colds, cough, hay fever, or sinus problems
without asking your prescriber or health care professional for advice.
Do not treat yourself for a fever or sore throat; check with your
prescriber or health care professional first.
Top

Possible Side effects of Losartan-Hydrochlorothiazide (Generic Hyzaar)
Side effects of Hyzaar that should be reported to your prescriber or
health care professional as soon as possible:

Rare or uncommon Side effects of Hyzaar:
difficulty breathing, difficulty swallowing, hoarseness, or
 tightening of the throat

redness, blistering, peeling or loosening of the skin, including
 inside the mouth
swelling of your face, lips, tongue, hands, or feet

unusual rash, bleeding or bruising, or pinpoint red spots on the
 skin
Other Side effects of Hyzaar:

confusion, dizziness, lightheadedness or fainting spells
decreased amount of urine passed

decreased sexual function
fast or uneven heart beat, palpitations, or chest pain

fever or chills
irregular heartbeat

muscle cramps
stomach pain

vomiting
unusual tiredness or weakness

worsened gout pain
yellowing of the eyes or skin

Side effects of Hyzaar that should be reported to your prescriber or
health care professional if they continue or are bothersome:
cough

diarrhea
headache

increased sensitivity to the sun
nausea

tiredness or fatigue
Top

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