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Vytorin ======= Vytorin, which is a combination of two drugs: ezetimibe (marketed as Zetia in the United States) and the statin drug simvastatin (marketed as Zocor). Vytorin is prescribed for the treatment of dyslipidemia, which occurs when the amount of lipids in the bloodstream is disrupted. In the U.S., this usually involves an elevation of lipids due to diet or lifestyle. The Zocor in Vytorin is designed to combat the disease by blocking an enzyme in the blood that enables the body's production of cholesterol, while the Zetia is meant to reduce the amount of cholesterol that the body absorbs from food.
However, an extensive study completed in mid 2006, and released in January 2008 has shown that taking Vytorin had no benefit on the buildup of artery plaque when compared with patients taking only Zocor. This finding is significant, as Vytorin is three times more expensive than the generic version of Zocor (simvastatin). The manufacturer has disputed the study's findings, but within weeks of the study's release a class action lawsuit has already been filed against Merck and Schering-Plough. The Vytorin lawsuit alleges that the companies have known since 2006 that their drug was no more effective than the cheaper generic Zocor, despite leading consumers to believe the opposite. Fast Facts ----------
Name: Vytorin
Generic: Ezetimibe and Simvastatin
Manufacturer: Merck/Schering-Plough
Date approved: July 23, 2004
Status: Prescription only
Approved uses: Approved for the treatment of dyslipidemia, a disruption in the amount of lipids in the blood.
Off-Label uses: Has a possible off-label ability to eliminate blood vessel inflammation often associated with being the cause of high BP
Side effects: Headache and muscle pain. High doses of Simvastatin, a medication used in Vytorin, has been linked to muscle damage.
Related topics: Zetia, Zocor
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Merck Agrees to Pay $41.5 Million in Vytorin Class Action Lawsuit ----------------------------------------------------------------- Merck Agrees to pay $41.5 million in Vytorin Class Action Lawsuit The makers of the popular cholesterol drugs, Vytorin and Zetia, have agreed to pay $41.5 million in a Vytorin class action lawsuit.... read more
Three Studies Report Possible Vytorin-cancer Link ------------------------------------------------- Three studies Report Possible Vytorin -cancer link Three separate studies of the cholesterol-lowering combination drug Vytorin have reported results that show a possible connection between the drug... read more
View the Vytorin Main Articles page here ---------------------------------------------------------------------
MSN Newsfeeds Related to Vytorin -------------------------------- Cholesterol drug flap hurts sales
Capitol Hill Watch Rep. Stupak Works To Increase FDA Oversight ... View the Vytorin MSN Newsfeeds page here
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What Frazier’s Promotion Means For Merck « Forbes.com's The Science Business Navigenics Adds Genetic Drug Response Results to Service; Offers PGx Wallet Card Pharmacogenomics Reporter DxPGx GenomeWeb
View the Vytorin News Articles page here ---------------------------------------------------------------------
Wikipedia Entries Related to Vytorin ------------------------------------ Ezetimibe/simvastatin
Ezetimibe View the Vytorin Wikipedia Entries page here
--------------------------------------------------------------------- Books Related to Vytorin ------------------------
Zetia & Vytorin case study: successfully challenging the statin market Nuevo medicamento contra el colesterol.(Vytorin): An article from: Siempre!
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