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Fact sheet N°210
Revised May 2001
Arsenic in drinking water
=========================

Arsenic may be found in water which has flowed through arsenic-rich
rocks. Severe health effects have been observed in populations
drinking arsenic-rich water over long periods in countries world-wide.
Source

Arsenic is widely distributed throughout the earth's crust.
Arsenic is introduced into water through the dissolution of
 minerals and ores, and concentrations in groundwater in some areas
 are elevated as a result of erosion from local rocks.

Industrial effluents also contribute arsenic to water in some
 areas.
Arsenic is also used commercially e.g. in alloying agents and wood
 preservatives.

Combustion of fossil fuels is a source of arsenic in the
 environment through disperse atmospheric deposition.
Inorganic arsenic can occur in the environment in several forms
 but in natural waters, and thus in drinking-water, it is mostly
 found as trivalent arsenite (As(III)) or pentavalent arsenate (As
 (V)). Organic arsenic species, abundant in seafood, are very much
 less harmful to health, and are readily eliminated by the body.

Drinking-water poses the greatest threat to public health from
 arsenic. Exposure at work and mining and industrial emissions may
 also be significant locally.
Effects

Chronic arsenic poisoning, as occurs after long-term exposure
 through drinking- water is very different to acute poisoning.
 Immediate symptoms on an acute poisoning typically include
 vomiting, oesophageal and abdominal pain, and bloody "rice water"
 diarrhoea. Chelation therapy may be effective in acute poisoning
 but should not be used against long-term poisoning.
The symptoms and signs that arsenic causes, appear to differ
 between individuals, population groups and geographic areas. Thus,
 there is no universal definition of the disease caused by arsenic.
 This complicates the assessment of the burden on health of
 arsenic. Similarly, there is no method to identify those cases of
 internal cancer that were caused by arsenic from cancers induced
 by other factors.

Long-term exposure to arsenic via drinking-water causes cancer of
 the skin, lungs, urinary bladder, and kidney, as well as other
 skin changes such as pigmentation changes and thickening
 (hyperkeratosis).
Increased risks of lung and bladder cancer and of
 arsenic-associated skin lesions have been observed at
 drinking-water arsenic concentrations of less than 0.05 mg/L.

Absorption of arsenic through the skin is minimal and thus
 hand-washing, bathing, laundry, etc. with water containing arsenic
 do not pose human health risk.
Following long-term exposure, the first changes are usually
 observed in the skin: pigmentation changes, and then
 hyperkeratosis. Cancer is a late phenomenon, and usually takes
 more than 10 years to develop.

The relationship between arsenic exposure and other health effects
 is not clear-cut. For example, some studies have reported
 hypertensive and cardiovascular disease, diabetes and reproductive
 effects.
Exposure to arsenic via drinking-water has been shown to cause a
 severe disease of blood vessels leading to gangrene in China
 (Province of Taiwan), known as 'black foot disease'. This disease
 has not been observed in other parts of the world, and it is
 possible that malnutrition contributes to its development.
 However, studies in several countries have demonstrated that
 arsenic causes other, less severe forms of peripheral vascular
 disease.

According to some estimates, arsenic in drinking-water will cause
 200,000 -- 270,000 deaths from cancer in Bangladesh alone (NRC,
 1998; Smith, et al, 2000).
Measurement

Accurate measurement of arsenic in drinking-water at levels
 relevant to health requires laboratory analysis, using
 sophisticated and expensive techniques and facilities as well as
 trained staff not easily available or affordable in many parts of
 the world.
Analytical quality control and external validation remain
 problematic.

Field test kits can detect high levels of arsenic but are
 typically unreliable at lower concentrations of concern for human
 health. Reliability of field methods is yet to be fully evaluated.
Prevention and control

The most important remedial action is prevention of further exposure
by providing safe drinking- water. The cost and difficulty of reducing
arsenic in drinking-water increases as the targeted concentration
lowers. It varies with the arsenic concentration in the source water,
the chemical matrix of the water including interfering solutes,
availability of alternative sources of low arsenic water, mitigation
technologies, amount of water to be treated, etc.
Control of arsenic is more complex where drinking-water is obtained
from many individual sources (such as hand-pumps and wells) as is
common in rural areas. Low arsenic water is only needed for drinking
and cooking. Arsenic-rich water can be used safely for laundry and
bathing. Discrimination between high-arsenic and low-arsenic sources
by painting the hand-pumps (e.g. red and green) can be an effective
and low cost means to rapidly reduce exposure to arsenic when
accompanied by effective health education.

Alternative low-arsenic sources such as rain water and treated surface
water may be available and appropriate in some circumstances. Where
low arsenic water is not available, it is necessary to remove arsenic
from drinking-water:
The technology for arsenic removal for piped water supply is
 moderately costly and requires technical expertise. It is
 inapplicable in some urban areas of developing countries and in
 most rural areas world-wide.

New types of treatment technologies, including co-precipitation,
 ion exchange and activated alumina filtration are being
 field-tested.
There are no proven technologies for the removal of arsenic at
 water collection points such as wells, hand-pumps and springs.

Simple technologies for household removal of arsenic from water
 are few and have to be adapted to, and proven sustainable in each
 different setting.
Some studies have reported preliminary successes in using packets
 of chemicals for household treatment. Some mixtures combine
 arsenic removal with disinfection. One example, developed by the
 WHO/PAHO Pan American Center of Sanitary Engineering and
 Environmental Sciences in Lima, Peru (CEPIS), has proven
 successful in Latin America.

WHO's activities on arsenic
WHO's norms for drinking-water quality go back to 1958. The
International Standards for Drinking-Water established 0.20 mg/L as an
allowable concentration for arsenic in that year. In 1963 the standard
was re-evaluated and reduced to 0.05 mg/L. In 1984, this was
maintained as WHO's "Guideline Value"; and many countries have kept
this as the national standard or as an interim target. According to
the last edition of the WHO Guidelines for Drinking-Water Quality
(1993):

Inorganic arsenic is a documented human carcinogen.
0.01 mg/L was established as a provisional guideline value for
 arsenic.

Based on health criteria, the guideline value for arsenic in
 drinking-water would be less than 0.01mg/L.
Because the guideline value is restricted by measurement
 limitations, and 0.01 mg/L is the realistic limit to measurement,
 this is termed a provisional guideline value.

The WHO Guidelines for Drinking-water Quality is intended for use as a
basis for the development of national standards in the context of
local or national environmental, social, economic, and cultural
conditions.
The summary of an updated International Programme on Chemical Safety
Environmental Health Criteria Document on Arsenic published by WHO is
available at http://www.who.int/pcs/pubs/pubehcnum.html. It
addresses all aspects of risks to human health and the environment.
The full text will be published in late 2001.

A UN report on arsenic in drinking-water has been prepared in
cooperation with other UN agencies under the auspices of an
inter-agency coordinating body (the Administrative Committee on
Coordination's Sub-committee on Water Resources. It provides a
synthesis of available information on chemical, toxicological,
medical, epidemiological, nutritional and public health issues;
develops a basic strategy to cope with the problem and advises on
removal technologies and on water quality management. The draft of the
report is available at
http://www.who.int/watersanitationhealth/dwq/arsenic3/en/
Information on arsenic in drinking-water on a country-by-country basis
is being collected and will be added to the UN report and made
available on the web site.

As part of WHO's activities on the global burden of disease, an
estimate of the disease burden associated with arsenic in
drinking-water is in preparation. A report entitled "Towards an
assessment of the socioeconomic impact of arsenic poisoning in
Bangladesh" was released in 2000.
A United Nations Foundation grant for 2.5 million approved in July
2000, will enable UNICEF and WHO to support a project to provide clean
drinking-water alternatives to 1.1 million people in three of the
worst affected sub-districts in Bangladesh. The project utilizes an
integrated approach involving communication, capacity building for
arsenic mitigation of all stakeholders at subdistrict level and below,
tube-well testing, patient management, and provision of alternative
water supply options.

Urgent requirements
Large-scale support to the management of the problem in developing
 countries with substantial, severely affected populations.

Simple, reliable, low-cost equipment for field measurement.
Increased availability and dissemination of relevant information.

Robust affordable technologies for arsenic removal at wells and in
 households.
Global situation

The delayed health effects of exposure to arsenic, the lack of common
definitions and of local awareness as well as poor reporting in
affected areas are major problems in determining the extent of the
arsenic-in-drinking-water problem.
Reliable data on exposure and health effects are rarely available, but
it is clear that there are many countries in the world where arsenic
in drinking-water has been detected at concentration greater than the
Guideline Value, 0.01 mg/L or the prevailing national standard. These
include Argentina, Australia, Bangladesh, Chile, China, Hungary,
India, Mexico, Peru, Thailand, and the United States of America.
Countries where adverse health effects have been documented include
Bangladesh, China, India (West Bengal), and the United States of
America. Examples are:

Seven of 16 districts of West Bengal have been reported to have
 ground water arsenic concentrations above 0.05 mg/L; the total
 population in these seven districts is over 34 million (Mandal, et
 al, 1996) and it has been estimated that the population actually
 using arsenic-rich water is more than 1 million (above 0.05 mg/L)
 and is 1.3 million (above 0.01 mg/L) (Chowdhury, et al, 1997).
According to a British Geological Survey study in 1998 on shallow
 tube-wells in 61 of the 64 districts in Bangladesh, 46% of the
 samples were above 0.010 mg/L and 27% were above 0.050 mg/L. When
 combined with the estimated 1999 population, it was estimated that
 the number of people exposed to arsenic concentrations above 0.05
 mg/l is 28-35 million and the number of those exposed to more than
 0.01 mg/l is 46-57 million (BGS, 2000).

Environment Protection Agency of The United States of America has
 estimated that some 13 million of the population of USA, mostly in
 the western states, are exposed to arsenic in drinking- water at
 0.01 mg/L, although concentrations appear to be typically much
 lower than those encountered in areas such as Bangladesh and West
 Bengal. (USEPA, 2001)
Arsenic in Bangladesh

In Bangladesh, West Bengal (India) and some other areas, most
drinking-water used to be collected from open dug wells and ponds with
little or no arsenic, but with contaminated water transmitting
diseases such as diarrhoea, dysentery, typhoid, cholera and hepatitis.
Programmes to provide "safe" drinking-water over the past 30 years
have helped to control these diseases, but in some areas they have had
the unexpected side-effect of exposing the population to another
health problem - arsenic.
Arsenic in drinking-water in Bangladesh is attracting much attention
for a number of reasons. It is a new, unfamiliar problem to the
population, including concerned professionals. There are millions of
people who may be affected by drinking arsenic-rich water. Last, but
not least, fear for future adverse health effects as a result of water
already consumed.

Background
In recent years, extensive well drilling programme has contributed
 to a significant decrease in the incidence of diarrhoeal diseases.

It has been suggested that there are between 8-12 million shallow
 tube-wells in Bangladesh. Up to 90% of the Bangladesh population
 of 130 million prefer to drink well water. Piped water supplies
 are available only to a little more than 10% of the total
 population living in the large agglomerations and some district
 towns.
Until the discovery of arsenic in groundwater in 1993, well water
 was regarded as safe for drinking.

It is now generally agreed that the arsenic contamination of
 groundwater in Bangladesh is of geological origin. The arsenic
 derives from the geological strata underlying Bangladesh.
Situation

The most commonly manifested disease so far is skin lesions. Over
 the next decade, skin and internal cancers are likely to become
 the principal human health concern arising from arsenic.
According to one estimate, at least 100,000 cases of skin lesions
 caused by arsenic have occurred and there may be many more (Smith,
 et al, 2000).

The number of people drinking arsenic-rich water in Bangladesh has
 increased dramatically since the 1970s due to well-drilling and
 population growth.
The impact of arsenic extends from immediate health effect to
 extensive social and economic hardship that effects especially the
 poor. Costs of health care, inability of affected persons to
 engage in productive activities and potential social exclusion are
 important factors.

The national standard for drinking-water in Bangladesh is 0.05
 mg/L, same as in India.
District and sub-district health officials and workers lack
 sufficient knowledge as to the identification and prevention of
 arsenic poisoning.

The poor availability of reliable information hinders action at
 all levels and may lead to panic, exacerbated if misleading
 reports are made. Effective information channels have yet to be
 established to those affected and concerned.
Remedial actions

Within Bangladesh, a number of governmental technical and advisory
 committees have been formed and a co-ordinating mechanism
 established among the interested external support agencies. These
 committees include the Governmental Arsenic Co-ordinating
 Committee headed by the Minister of Health & Family Welfare (MHFW)
 and several technical committees. One of the positive outcomes of
 this collaboration (including work with local institutes) has been
 the testing of new types of treatment technologies.
So far, many initiatives have focused on water quality testing and
 control with a view to supplying arsenic-free drinking-water,
 thereby reducing the risk of further arsenic-related disease. The
 amount of testing required and the need to provide effective
 feedback to those using well water, suggest use of field testing
 kits.

Only a few proven sustainable options are available to provide
 safe drinking-water in Bangladesh. These include: obtaining
 low-arsenic groundwater through accessing safe shallow groundwater
 or deeper aquifers (greater than 200 m); rain water harvesting;
 pond-sand-filtration; household chemical treatment; and piped
 water supply from safe or treated sources.
For more information contact:

WHO Media centre
Telephone: +41 22 791 2222
E-mail: mediainquiries@who.int
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