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EUTHYROID SICK SYNDROME

First broadcast on www.provet.co.uk

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This information is provided by Provet for educational purposes only.

You should seek the advice of your veterinarian if your pet is ill as
only he or she can correctly advise on the diagnosis and recommend the
treatment that is most appropriate for your pet.

Euthyroid Sick Syndrome is the term given to abnormally low thyroxine
(T4) concentrations in the blood, even though thyroid function is
actually normal. For this reason a diagnosis of hypothyroidism should
be confirmed by performing a Thyroid Stimulating Hormone stimulation
test, and should not be based on low basal T4 concentrations alone.

The precise mechanism that leads to abnormally low thyroxine (T4)
concentrations in the blood are not fully understood, but it may be
associated with low circulating protein concentrations or reduced
binding of T4 to blood proteins. In any event the following is an
alphabetical list of some of the clinical conditions which can cause a
low T4 even though thyroid function is normal :

Autoimmune hemolyticanaemia

Cardiomyopathy

Diabetes mellitus

Generalised skin disease (eg demodex)

Heart failure (congestive)

Hepatitis (chronic active)

Infections

Intervertebral disc protrusion

Liver failure (eg cirrhosis)

Lymphosarcoma

Malabsorption

Megaoesophagus

Nephrotic syndrome

Polyneuropathy

Protein-losing enteropathy

Renal failure (chronic)

Starvation

Systemic lupus erythematosus (SLE)

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