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A B C D E F G H I J K L M N O P R S T U V W Y
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Degenerative Disc Disease
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What is the Definition of Degenerative Disc Disease?
Description of Degenerative Disc Disease

Causes of Degenerative Disc Disease
Symptoms of Degenerative Disc Disease

Treatment for Degenerative Disc Disease
What Questions to ask Your Doctor About Degenerative Disc Disease?

What is the Definition of Degenerative Disc Disease?
Article updated and reviewed by Scott J. Luhmann, MD, Instructor in
Surgery, Department of Orthopaedic Surgery, Washington University
School of Medicine on June 6, 2005.

Degenerative disc disease refers to wear changes in the individual
discs of the spine in any part of the spine.
Spondylosis is another term for degenerative disc disease.

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Description of Degenerative Disc Disease

DDD can affect any part of the spine, although common sites are the
lumbar (lower back) and cervical (neck) spine; thoracic DDD is very
uncommon.
Radiographic (x-ray) findings of DDD are a narrower disc space and
some osteophyte (bony outgrowth of spur) formation. As people age,
these changes tend to show up on the radiographs of most men and
women. However, the first imaging modality to detect changes of DDD is
MRI (magnetic resonance imaging), even before plain radiographs. Loss
of water content (hydration) in the invertebral disc is an early
finding, which is followed by narrowing of the disc space. People in
the 20?s and 30?s may already have changes to their discs but no
clinical symptoms. As the aging processes continues, the prevalence of
DDD increases.

In the early phases of DDD, spontaneous or post-traumatic tears,
degeneration, fibrosis, and collapse of the disc may lead to failure
of mechanical function. This is associated with low back pain and
possible leg pain if there is nerve root impingement (radiculopathy).
As DDD progresses, there is ligamentous buckling and osteophyte
development which can cause narrowing of the space for the spinal cord
and nerve roots. Lumbar spinal stenosis is the narrowing of the neural
canal and foramina to an extent that results in compression of the
lumbosacral nerve roots or cauda equina. Acquired lumbar stenosis is
caused primarily be degenerative disease of the spine. However, a
congenitally narrow or small spinal canal is a common finding; when
present, it requires less disc degeneration, smaller disc herniation,
or osteophytes to cause symptoms.

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Causes of Degenerative Disc Disease

Degenerative disc disease can result from trauma (either acute or
chronic/repetitive), infection, or the natural processes of aging. It
can euphemistically be referred to as the ?grey hairs of the spine?.
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Symptoms of Degenerative Disc Disease
The process of degeneration of the spine may lead to local pain,
stiffness, and restricted activity. If there is disc herniation or
rupture, one may also have leg/groin/knee pain dependent upon which
nerve root is affected.

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Treatment for Degenerative Disc Disease

Primary management for DDD is non-operative and includes nonsteroidal
anti-inflammatory medications (NSAIDs) and exercise programs to
strengthen abdominal and spinal musculature, improve aerobic fitness,
and reduce lumbar lordosis (swayback).
Surgical intervention is an option when nonoperative medical
management fails to adequately relieve the intolerable pain during
activities of daily living which is individual-specific. It should
also be considered in patients with initial signs and symptoms of
progressive neurologic deterioration, specifically numbness or muscle
weakness.

Classical surgical treatment for DDD which has failed nonoperative
management is a spine fusion. However, advances in disc replacement
technologies have made this technique a viable option for many
individuals. Early investigations have demonstrated lumbar disc
replacements have had outcomes equivalent to spine fusion. Not all
individuals with DDD are good candidates for disc replacement surgery.
Concomitant spinal deformity (scoliosis, kyphosis), history of spinal
infection, posterior spinal arthritis, and multilevel disc disease are
relative or absolute contraindications.
For those individuals who are not candidates for lumbar disc
replacement, lumbar spine fusions have had good short-term and
long-term outcomes. Fusion involve creating a solid bony connection
between two or more vertebrae anteriorly, posteriorly, or both.

In a spine fusion procedure, the surgeon joins two or more adjacent
vertebrae. Bone taken from other parts of the body, usually the pelvis
just above the hip joint, is placed across the vertebrae. Plugs of
bone shaped like hockey pucks or cages made of metal or plastic are
used between the vertebrae anteriorly. Posteriorly the bone is ground
up into small pieces and laid down over the spine. The vertebrae and
bone graft grow together as healing progresses, eventually forming a
single unit without motion across them.
If the spine is in overall good position, spinal implants may not be
necessary. So while not all spinal fusions require implants, many
patients whose spines are weakened by injury or disease or whose
deformities must be corrected are treated with internal fixation or
spinal implants. If the spine needs to be placed and maintained in a
new position, spinal implants will typically be necessary. The
implants can include rods, screws, and hooks to fixate and stabilize
the spine. Various types of implants are used depending on the problem
that required the fusion, the patient's age, and the surgeon?s
judgment. These implants are usually left implanted indefinitely to
minimize the possible loss of spinal alignment. The development of a
spine fusion may take up to one year during which time physical
activity may be limited and a spine brace may be recommended.

Fusion surgery is inherently more complicated, more painful, and
riskier than procedures such as discectomy and laminectomy. There is
no consensus in the medical community as to the appropriate
indications for fusion surgery.
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What Questions to ask Your Doctor About Degenerative Disc Disease?
What is the problem with the lumbar spine?

Is there significant narrowing and compression?
What treatments do you recommend?

What operative treatments are options?
Is spinal fusion preferable to laminectomy and other procedures?

Will spinal implants be used? If so, what kind and what is their
purpose?
What are the possible complications?

What are the chances the preoperative symptoms will be improved or
eliminated?
 

Editorial review provided by VeriMed Healthcare Network.
 

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