Information about nexium side effects
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See All Home › Drugs by Condition › G › Gastroesophageal Reflux Disease › Nexium › Side Effects Print Save or Share
Nexium Side Effects =================== Generic Name: esomeprazole
Please note - some side effects for Nexium may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088). Side Effects of Nexium - for the Consumer -----------------------------------------
Nexium I.V. All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Nexium I.V.:
Constipation; diarrhea; dry mouth; gas; headache; nausea; pain, swelling, or redness at the injection site; stomach pain. Seek medical attention right away if any of these SEVERE side effects occur when using Nexium I.V.:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); chest pain; fast heartbeat; fever, chills, or sore throat; red, swollen, blistered, or peeling skin; unusual bruising or bleeding; unusual tiredness. Nexium Delayed-Release Capsules
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Nexium Delayed-Release Capsules: Constipation; diarrhea; dry mouth; gas; headache; nausea; stomach pain.
Seek medical attention right away if any of these SEVERE side effects occur when using Nexium Delayed-Release Capsules: Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); chest pain; dark urine; fast heartbeat; fever or chills; persistent sore throat; red, swollen, blistered, or peeling skin; severe stomach pain; unusual bruising or bleeding; unusual tiredness; yellowing of the eyes or skin.
Nexium Suspension All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Nexium Suspension:
Constipation; diarrhea; dry mouth; gas; headache; nausea; stomach pain. Seek medical attention right away if any of these SEVERE side effects occur when using Nexium Suspension:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); chest pain; dark urine; fast heartbeat; fever or chills; persistent sore throat; red, swollen, blistered, or peeling skin; severe stomach pain; unusual bruising or bleeding; unusual tiredness; yellowing of the eyes or skin. Top
Side Effects by Body System --------------------------- Gastrointestinal
Gastrointestinal (GI) side effects have included bowel irregularity, aggravated constipation, dyspepsia, dysphagia, dysplasia, epigastric pain, eructation, esophageal disorder, frequent stools, gastroenteritis, GI hemorrhage, rectal disorder, increased appetite, anorexia, ulcerative stomatitis, and vomiting. Pancreatitis has also been reported. Nervous system
Nervous system side effects have included confusion, dizziness, hypoesthesia, insomnia, migraine aggravation, paresthesia, sleep disorder, somnolence, tremor, and vertigo. Cardiovascular
Cardiovascular side effects have included hypertension, angioedema, tachycardia, chest pain, and substernal chest pain. Musculoskeletal
Musculoskeletal side effects have included arthralgia, aggravation of arthritis, arthropathy, cramps, fibromyalgia syndrome, hernia, hypertonia, polymyalgia rheumatica, and back pain. Myalgia and hip fracture have also been reported. An increased risk of hip fracture has been reported in a cohort study. The risk was significantly increased among patients prescribed long-term high PPIs.
Hematologic Hematologic side effects have included anemia, hypochromic anemia, cervical lymphadenopathy, epistaxis, leukocytosis, leukopenia, and thrombocytopenia. Agranulocytosis and pancytopenia have also been reported.
Hepatic Hepatic side effects have included bilirubinemia, abnormal hepatic function, and increase in SGOT and SGPT. Hepatitis, with or without jaundice, has also been reported.
Metabolic Metabolic side effects have included glycosuria, hyperuricemia, hyponatremia, increased alkaline phosphatase, excessive thirst, vitamin B12 deficiency, and weight increase/decrease.
Genitourinary Genitourinary side effects have included abnormal urine, albuminuria, cystitis, dysuria, hematuria, micturition frequency, moniliasis, genital moniliasis, impotence, dysmenorrhea, menstrual disorder, vaginitis, and polyuria.
Psychiatric A 42-year-old female with previously normal sexual function experienced loss of libido during esomeprazole therapy. She had been prescribed 40 mg esomeprazole twice daily for one month for symptoms of acid reflux disease. Over a 10 week period, she experienced a decline in sexual function until she could no longer respond sexually. After discontinuation of esomeprazole, her symptoms improved but did not return to what she considered normal.
Psychiatric side effects have included apathy, confusion, aggravated depression, and nervousness. At least one case of loss of libido has been reported. Respiratory
Respiratory side effects have included aggravated asthma, coughing, dyspnea, larynx edema, pharyngitis, rhinitis, and sinusitis. General
General side effects including hot flushes, fatigue, fever, flu-like disorder, leg edema, malaise, pain, earache, tinnitus, otitis, parosmia, taste loss, taste perversion, and enlarged abdomen have been reported. Ocular
Ocular side effects have included abnormal vision, conjunctivitis, and visual field defect. Blurred vision has also been reported. Dermatologic
Dermatologic side effects have included acne, dermatitis, pruritus, erythematous rash, maculopapular rash, skin inflammation, and increased sweating. Alopecia and erythema multiforme have also been reported. Duodenitis, esophagitis, esophageal stricture, esophageal ulceration, esophageal varices, gastric ulcer, gastritis, hernia, benign polyps or nodules, Barrett's esophagus, and mucosal discoloration have also been reported. Endocrine
Endocrine side effects have included goiter. Hypersensitivity
Hypersensitivity side effects have rarely included allergic reactions (less than 1%). Toxic epidermal necrolysis (some cases fatal) and Stevens-Johnson syndrome have also been reported. Immunologic
Immunologic side effects have included anaphylactic reaction or shock. Renal
A 63-year-old female with dyspepsia experienced acute interstitial nephritis coincident with esomeprazole therapy. She presented to the hospital with a 1-month history of nausea and intermittent vomiting. Three weeks before presentation, she was empirically prescribed esomeprazole for the treatment of dyspepsia. A week before presentation, she stopped taking this drug, as she suspected it was exacerbating the malaise, nauseas, and vomiting. On day 4 of admission, a renal biopsy showed acute interstitial nephritis. Prednisolone therapy was continued for 4 weeks. Supportive dialysis was needed for 4 days, by which time renal function had improved. However, at follow-up 8 months later, serum creatinine levels remained abnormal. Renal side effects including at least two cases of interstitial nephritis have been reported.
Top More Nexium resources ---------------------
Nexium Advanced Consumer (Micromedex) - Includes Dosage Information Nexium Detailed Consumer Information (PDR)
Nexium Consumer Overview Nexium Delayed-Release Capsules MedFacts Consumer Leaflet (Wolters Kluwer)
Esomeprazole Professional Patient Advice (Wolters Kluwer) Esomeprazole MedFacts Consumer Leaflet (Wolters Kluwer)
Nexium Prescribing Information (FDA) Nexium I.V. Consumer Overview
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