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| Runtime: 0m 28s | Views: 4343 Added: 05-01-2008 From: sertan (Send |
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Description (Edit): This conceptual mode of action animation is of the drug Viagra developed by Pfizer pharmaceuticals. Viagra functions by inhibiting the enzyme phosphodiesterase-5 PDE-5. Under normal conditions PDE-5 converts cyclic-GMP cGMP into GMP shown as green and red spheres. Viagra selectively inhibits PDE-5 by blocking the site where cGMP binds. As a result, the cellular concentration of cGMP increases, causing an increase in blood flow to the corpus cavernosum. www.scianafilms.com less...Description (Edit): This conceptual mode of action animation is of the drug Viagra developed by Pfizer pharmaceuticals. Viagra functions by inhibiting the enzyme phosphodiesterase-5 PDE-5. Under normal conditions PDE-5 converts cyclic-GMP cGMP into GMP shown as green and red spheres. Viagra selectively inhibits PDE-5 by blocking the site where cGMP binds. As a result, the cellular concentration of cGMP increases, causing an increase in blood flow to the corpus cavernosum. www.scianafilms.com more.... Channels: Scientific Animations Others Medical
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