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Numbness:
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PARESTHESIAS OF THE LOWER EXTREMITY (Algorithmic Diagnosis of
 Symptoms and Signs)

PARESTHESIAS OF THE UPPER EXTREMITY (Algorithmic Diagnosis of
 Symptoms and Signs)
GAIT DISTURBANCES (Algorithmic Diagnosis of Symptoms and
 Signs)

Paresthesias (In a Page: Signs and Symptoms)
Paresthesias (In A Page: Pediatric Signs and Symptoms)

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Diagnostic Tests for Numbness
=============================

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Diagnostic Test list for Numbness:
----------------------------------

The list of diagnostic tests mentioned in various sources as used in
the diagnosis of Numbness includes:
General appearance - abnormal posture, muscle wasting, abnormal
 limb movements.

Mental state examination - including appearance, behavior, rate
 and continuity of speech, mood, affect, thought content, evidence
 of any hallucinations or abnormal beliefs, orientation to time,
 place and person, attention and concentration, short-term memory,
 insight and judgement. May help detect and evaluate anxiety and
 panic states which may cause rapid breathing (hyperventilation)
 and consequent numbness around the lips, lightheadedness and
 tingling in the extremities.
Physical examination

Examine for physical signs of low calcium including Chvostek's
 sign (gentle tapping over the facial nerve causes twitching of
 the facial muscles) and Trousseau's sign (inflation of the
 blood pressure cuff above diastolic blood pressure for 3
 minutes causes muscular contraction of the fingers and wrist)
Examination of cranial nerves ( if affected would suggest a
 diagnosis of cerebrovascular disease , a mass in the brain,
 migraine or multiple sclerosis)

Test muscle tone, power, reflexes and co-ordination of upper
 limbs
Test sensation of upper limbs ( including pain , touch ,
 temperature and vibration sensation)

Examine each nerve of the upper limb (including radial ,
 median, ulnar nerve and also brachial plexus)
Test muscle tone, power, reflexes and co-ordination of lower
 limbs

Test sensation of lower limbs ( including pain , touch ,
 temperature and vibration sensation)
Examine each nerve of the lower limb (including lateral
 cutaneous nerve of the thigh, femoral nerve, sciatic nerve and
 common peroneal nerve)

Feel the pulses in the legs - if reduced or absent should
 suggest peripheral atherosclerosis (hardening of the arteries)
 or obstruction of the abdominal aorta and its branches by
 atherosclerosis.
Examine for a positive straight leg raising test
 (straightening the leg at the knee while lying on a bed
 causing pain in thigh, buttock and back) and/or a reduced
 ankle reflex- indicates herniated disk f L4-5 or L5-S1, lumbar
 spondylosis, spinal stenosis, cauda equina tumor or
 spondylolisthesis

Examine for a positive femoral stretch test (with the person
 laying on their stomach, flex knee with hip lifted in
 extension causes pain in the front of the thigh and the back)
 or a decreased knee jerk - indicates a herniated disk of L3-4
 or L2-3 or lumbar spondylosis.
Blood tests

Full blood test and ESR
Electrolytes

Calcium level to detect hypocalcemia which can cause facial
 numbness
Elevated phosphate levels may cause hypocalcaemia

Low parathyroid hormone may cause hypocalcemia
Low Vitamin D metabolite levels may cause hypocalcemia

Renal function tests to detect chronic renal failure which may
 cause hypocalcemia
Blood glucose and/or glucose tolerance test to rule out
 diabetes if peripheral neuropathy or peripheral nerve lesions
 are present

Arthritis screen (including Rheumatoid factor, ANA, ENA and ds
 DNA autoantibodies)
B12 and folic acid levels

Thyroid function tests to rule out hypothyroidism (which may
 cause carpal tunnel syndrome) and hyperthyroidism
Serum protein electrophoresis to diagnose various collagen
 vascular diseases that may cause neuropathy

Syphilis serology, if indicated
HIV test, if indicated

Lead or arsenic levels, if suspect lead or arsenic neuropathy
Urine tests

Urinalysis
Porphyrins and porphobilinogen to rule out Porphyria

24 hour urinary calcium
Radiological investigations (depending on area that is numb)

X-Ray of the lumbosacral spine
CT Scan of the lumbosacral spine

MRI Scan of the lumbosacral spine, may be necessary
Myelography may be useful when contemplating surgery

Neck X-ray (look for cervical rib which may cause thoracic
 outlet syndrome
Upper Thoracic spine X-Ray

Elbow , forearm, Shoulder X-ray
Wrist and Hand X-Ray

CT Scan or MRI of Cervical spine, if there is numbness of the
 upper limb(s) but nil numbness of the face or there are
 cranial nerve signs; can detect nerve root entrapment in the
 intervertebral foramina of the cervical spine or a disc
 prolapse
CT Brain or brain stem if there is numbness of an extremity
 and also numbness of the face or cranial nerve signs to detect
 cerebrovascular disease or mass in brain such as a tumour or
 abscess

MRI Brain and Spinal cord, if CT Scan is not helpful or
 inconclusive; or to detect multiple sclerosis
X-ray and CT scan of petrous temporal bone, if facial
 numbness, a history of trauma and have 7th nerve palsy

X-Ray of paranasal sinuses to detect infection which may cause
 cavernous sinus thrombosis and facial numbness
Carotid ultrasound scan, if stroke is suspected

Cerebral angiogram, if suspect cavernous venous thrombosis
Nerve conduction velocity study - to establish the presence of a
 neuropathy.

Electromyelogram (EMG) - to establish the presence of a neuropathy
 such as entrapment syndromes of peripheral nerves.
Spinal tap - if suspect multiple sclerosis, Guillain-Barre
 syndrome or neurosyphilis.

Electrophysiological tests such as visual-evoked response (VER) -
 may be required to diagnose Multiple sclerosis.
Lymph node biopsy - if sarcoidosis is suspected.

Muscle biopsy - if suspect various collagen diseases.
Home Diagnostic Testing
-----------------------

These home medical tests may be relevant to Numbness causes:
Diabetes: Related Home Testing:

Home Diabetes Testing
Home Blood Glucose Test Kits

Home Urine Glucose Tests
Home Urine Ketone Tests

Home Diabetes HbA1c Tests
Home Microalbumin Tests (Kidney)

Home Urine Protein Tests (Kidney)
Home Kidney Health Tests

Home Eye Health Tests
Nerve Neuropathy: Related Home Testing:

Home Diabetes Test Kits
Home Blood Glucose Testing Kits

Brain & Neurological Disorders: Related Home Testing:
ADHD -- Home Tests

Drug Screening Kits
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