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Viagra for women

Viagra for women
================
by Janet Casperson, BS, MSN, ANP-C

In animal studies, sildenafil (Viagra®) is reported to relax the
clitoral and vaginal smooth muscles. Some studies have reported
benefits with antidepressant-induced sexual dysfunction in women but
sildenafil is not approved by the FDA for the treatment of FSD.
Recent press release about a new drug for women:

Viagra For Women?
-----------------
November 18, 2009 – A drug originally developed as an anti-depressant
may work better as a female sexual boost. Researchers say it could be
a Viagra for women.

Three separate clinical studies have found that the anti-depressant,
flibanserin, can increase libido in women who report a low sex drive.
Multiple clinical trials reported that women with hypoactive sexual
desire disorder who took 100 mg of flibanserin daily saw an increase
in their number of satisfactory sexual encounters, increased sexual
desire, and a reduction of distress associated with sexual
dysfunction.
“It’s essentially a Viagra-like drug for women in that diminished
desire or libido is the most common feminine sexual problem, like
erectile dysfunction is in men,” John M. Thorp Jr., McAllister
distinguished professor of obstetrics and gynecology at the University
of North Carolina at Chapel Hill School of Medicine and principle
North-American investigator, was quoted as saying.

The studies involved a total of 1,946 pre-menopausal women 18 years
and older, and randomly assigned women to either receive flibanserin
or a placebo. Particpants were followed four weeks prior to the study,
and four weeks after the study. Researchers found that a daily dose of
50 mg was too small to be effective, and that greatest improvement of
symptoms required 100 mg of flibanserin daily.
“These results point to a novel approach to pharmacologic treatment of
the sexual problem that plagues reproductive age women the most,"
Thorpe was quoted as saying.

Nine to 26 percent of American women are affected by hypoactive sexual
desire disorder.
SOURCE: Presented at the Congress of the European Society for Sexual
Medicine in Lyon, France, November 16, 2009.

References: Bibliography
August 2006
Posted August 2008
Updated November 30, 2009

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